bum (out), burden, dash, depress, get down, oppress, sadden, weigh down

ail, distress, troubleafflict, torment, torturedaunt, demoralize, discourage, dishearten, dismay, dispirit, unnerveagitate, bother, concern, discomfort, discompose, disquiet, disturb, exercise, freak (out), perturb, undo, unhinge, unsettle, upset, worry

brighten, buoy, cheer (up), gladden, lighten, rejoice

animate, enliven, invigorateassure, comfort, console, reassure, solace, sootheexcite, inspire, stimulateelate, exhilarateencourage, heartendelight, gratify, pleaseboost, elevate, lift, uplift