bums (out), burdens, dashes, dejects, depresses, gets down, oppresses, weighs down

ails, distresses, troublesafflicts, torments, torturesdaunts, demoralizes, discourages, disheartens, dismays, dispirits, gets down, unnervesagitates, bothers, concerns, discomforts, discomposes, disquiets, disturbs, exercises, freaks (out), perturbs, undoes, unhinges, unsettles, upsets, worries

brightens, buoys, cheers (up), gladdens, lightens, rejoices

animates, enlivens, invigoratesassures, comforts, consoles, reassures, solaces, soothesexcites, inspires, stimulateselates, exhilaratesencourages, heartensdelights, gratifies, pleasesboosts, elevates, lifts, uplifts